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Updated: Feb 6, 2026

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
Published on: October 31, 2017
Saturated Fatty Acids as Possible Key Amplifiers of Psoriatic Dermatitis
Satoshi Nakamizo1, Tetsuya Honda2, Kenji Kabashima3
1Singapore Immunology Network, Institute of Medical Biology and Skin Research Institute of Singapore, Agency for Science, Technology and Research, Singapore.
Abstract:
The association of obesity with psoriasis is well known, but the molecular link between these two entities is incompletely characterized. Herbert et al. report that dietary saturated fatty acids, rather than obesity itself, promote exacerbation of psoriasis in high fat diet-induced obesity. They also suggest that dietary manipulation could improve psoriasis.
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