Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Velocity and Position by Integral Method01:13

Velocity and Position by Integral Method

8.1K
If acceleration as a function of time is known, then velocity and position functions can be derived using integral calculus. For constant acceleration, the integral equations refer to the first and second kinematic equations for velocity and position functions, respectively.
Consider an example to calculate the velocity and position from the acceleration function. A motorboat is traveling at a constant velocity of 5.0 m/s when it starts to decelerate to arrive at the dock. Its acceleration is...
8.1K
Resonance02:52

Resonance

65.6K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
65.6K
Velocity and Position by Graphical Method01:34

Velocity and Position by Graphical Method

10.3K
Velocity and position can be calculated from the known function of acceleration as a function of time. The total area under the acceleration-time graph and the velocity-time graph gives the change in velocity and position, respectively. In the case of an airplane, its acceleration is tracked using the inertial navigation system. The pilot provides the input of the airplane's initial position and velocity before takeoff. The inertial navigation system then uses the acceleration data to...
10.3K
Position of Equilibrium in Acid-Base Reactions02:05

Position of Equilibrium in Acid-Base Reactions

15.1K
In any solution, the value of pKa indicates whether an acid is completely dissociated or not. A negative pKa corresponds to a stronger acid, whereas a positive pKa corresponds to a weaker acid. Consider the reaction between ammonia and an ethoxide ion. In this reaction, ethanol with a pKa of 15.9 is a stronger acid than ammonia with a pKa of 38. Recall that the strong acid forms a weak conjugate base, and a weak acid forms a strong conjugate base. Hence, the ethoxide ion is a weak base.
15.1K
Position-effect Variegation02:32

Position-effect Variegation

7.1K
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
7.1K
Position and Displacement01:31

Position and Displacement

26.2K
The position of an object defines its location relative to a convenient frame of reference at any particular time. A frame of reference is an arbitrary set of axes from which the position and motion of an object are described. Earth is often used as a frame of reference, and we often describe the position of an object as it relates to stationary objects on Earth. For example, a rocket launch could be described in terms of the position of the rocket with respect to Earth as a whole. On the other...
26.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polymer-Based Prism-Free Nanograting SPR Imaging Enables Multiplexed Detection and Single-Step Aptamer Binding Kinetics.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Dual-band spectral filter array integrated with a telecentric lens for real-time surface plasmon resonance sensing and imaging.

Nanophotonics (Berlin, Germany)·2025
Same author

Determination of Half-Maximal Inhibitory Concentration (IC<sub>50</sub>) of Drugs Using Contrast Surface Plasmon Imaging on Gold-Coated Periodic Nanowires.

Analytical chemistry·2025
Same author

Self-referenced Digital Spectral Chromatic Local Surface Plasmon Resonance in Ultrasensitive Severe Sepsis Interleukin-6 Detection.

ACS sensors·2025
Same author

Investigation of DNA Hybridization on Nano-Structured Plasmonic Surfaces for Identifying Nasopharyngeal Viruses.

Bioengineering (Basel, Switzerland)·2023
Same author

Biomimetic affinity sensor for the ultrasensitive detection of neonicotinoids.

Biosensors & bioelectronics·2023
Same journal

Smartphone-assisted fluorescence and colorimetric dual-mode sensor for visual quantitative detection of nitrite and nitrate in real samples.

Analytica chimica acta·2026
Same journal

Folding integrated all-paper photoelectrochemical immunoassay using annealed ZnO for point-of-care detection of ferritin.

Analytica chimica acta·2026
Same journal

Dual-mode electrochemical-SERS detection of chloramphenicol based on dual-signal enhancement.

Analytica chimica acta·2026
Same journal

Multi-screening of beta-lactam antibiotics in milk based on Fe<sub>3</sub>O<sub>4</sub>@phage/bacteria system and aggregation induced emission luminogen.

Analytica chimica acta·2026
Same journal

A porous phosphate-rich β-cyclodextrin polymer for efficient and broad-spectrum enrichment of antibiotics.

Analytica chimica acta·2026
Same journal

Corrigendum to "LUMIN: A novel algorithm for automated mixture quantification using 1D <sup>1</sup>H NMR spectra" [Analytica Chimica Acta 1411 (2026) 345639].

Analytica chimica acta·2026
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

2.8K

Resonant position tracking method for smartphone-based surface plasmon sensor.

Ming-Yang Pan1, Kuang-Li Lee1, Shu-Cheng Lo1

  • 1Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan.

Analytica Chimica Acta
|August 26, 2018
PubMed
Summary
This summary is machine-generated.

We developed a novel position-sensitive method for tracking surface plasmon resonance (SPR) signals in nanostructures. This technique offers improved noise reduction and enables sensitive, smartphone-based biosensing for protein interactions.

Keywords:
BiosensorsData analysisFano resonanceOptical sensorsSmartphoneSurface plasmon resonance

More Related Videos

Photodeposition of Pd onto Colloidal Au Nanorods by Surface Plasmon Excitation
06:58

Photodeposition of Pd onto Colloidal Au Nanorods by Surface Plasmon Excitation

Published on: August 15, 2019

7.9K
Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
10:41

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance

Published on: January 3, 2012

13.8K

Related Experiment Videos

Last Updated: Feb 6, 2026

Engineering Antiviral Agents via Surface Plasmon Resonance
13:00

Engineering Antiviral Agents via Surface Plasmon Resonance

Published on: June 14, 2022

2.8K
Photodeposition of Pd onto Colloidal Au Nanorods by Surface Plasmon Excitation
06:58

Photodeposition of Pd onto Colloidal Au Nanorods by Surface Plasmon Excitation

Published on: August 15, 2019

7.9K
Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
10:41

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance

Published on: January 3, 2012

13.8K

Area of Science:

  • Nanotechnology
  • Spectroscopy
  • Biophysics

Background:

  • Surface Plasmon Resonance (SPR) is a label-free optical technique for detecting molecular interactions.
  • Conventional SPR methods like wavelength or intensity interrogation face limitations in noise reduction and complexity.
  • Periodic metallic nanostructures offer enhanced sensitivity for SPR sensing applications.

Purpose of the Study:

  • To introduce a position-sensitive measurement method for tracking SPR resonant signals.
  • To demonstrate superior noise reduction and simplified calculations compared to existing methods.
  • To validate the application of this method for smartphone-based biosensing.

Main Methods:

  • Development of a position-sensitive resonant signal tracking technique.
  • Utilizing periodic metallic nanostructures (gold nanoslit arrays) as SPR sensors.
  • Employing a portable spectrometer for experimental measurements.
  • Theoretical comparison of shot noise and signal noise.

Main Results:

  • Achieved a limit of detection of 5.88 × 10-6 RIU with a 0.4 nm spectral resolution spectrometer.
  • Demonstrated superior noise reduction compared to conventional SPR interrogation methods.
  • Successfully detected protein-antibody interactions using a smartphone-based SPR system.

Conclusions:

  • The position-sensitive resonant tracking method provides significant noise reduction and computational simplicity.
  • This technique is suitable for developing portable, smartphone-based SPR biosensors.
  • Smartphone-based SPR sensing can achieve sensitive measurement of protein binding kinetics.