Longitudinal BMI Growth Curves for Surviving Preterm NICU Infants Based on a Large US Sample

Adrienne L Williamson1,2, Josip Derado1,3, Bradley J Barney1,4

  • 1Departments of Statistics and Analytical Sciences and.

Pediatrics
|August 26, 2018
PubMed

Insights

New longitudinal Body Mass Index (BMI) growth charts for preterm infants (24-36 weeks gestational age) reveal actual growth patterns over time, differing from existing cross-sectional data.

Area of Science:

  • Neonatalogy
  • Pediatric Growth Monitoring
  • Biostatistics

Background:

  • Existing growth curves for preterm infants lack longitudinal Body Mass Index (BMI) data.
  • Current BMI curves rely on cross-sectional data from different infant cohorts at each gestational age (GA).

Purpose of the Study:

  • To develop longitudinal BMI growth curves for preterm infants.
  • To provide a more accurate representation of infant body proportionality changes over time.

Main Methods:

  • Calculated BMI for 68,693 preterm infants (24-36 weeks GA).
  • Created longitudinal median curves stratified by sex, GA, and birth BMI quintiles.
  • Validated curves for fit, classification, and normality of z-scores.

Main Results:

  • Developed two sets of longitudinal BMI growth charts.
  • Longitudinal curves accurately reflect growth patterns, showing differences from cross-sectional data, especially post-nadir.
  • Observed variations in growth by GA and sex.

Conclusions:

  • New longitudinal BMI curves offer insights into preterm infant body proportionality.
  • These charts provide clinicians with data on dynamic growth changes in premature infants.
Abstract

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