Related Experiment Video
Updated: Feb 6, 2026

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
Published on: February 22, 2019
Three cases of spontaneous splenic rupture in malignant lymphoma
Jun Amaki1, Tatsuya Sekiguchi2, Shinichiro Hiraiwa3
1Division of Hematology/Oncology, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1143, Japan. junamaki@tokai-u.jp.
Abstract:
Spontaneous splenic rupture is a rare but often life-threatening condition. However, there is no consensus on appropriate management for this condition, due to its rarity. Here, we report three cases of malignant lymphoma with spontaneous splenic rupture. In each case, progression of splenic bleeding was rapid and complicated by malignant lymphoma. Spontaneous splenic rupture complicated by malignant lymphoma may cause exacerbation of anemia and hypovolemic shock. When splenic rupture is indicated by abdominal pain, tachycardia, or hypotension in a patient with splenomegaly, abdominal examination should be performed immediately, and emergency transcatheter arterial embolization and/or splenectomy should be considered.
Related Concept Videos
Spontaneity
Spontaneous and Induced Mutations
Effects of Temperature on Free Energy
Second Law of Thermodynamics
Gibbs Free Energy
Solution Formation
This selective...

