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Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption
Published on: June 20, 2025
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Epigenetic changes due to physical activity
Sadegh Rezapour1, Mustafa Shiravand2, Mahnaz Mardani3
1Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Biotechnology and Applied Biochemistry
|August 26, 2018
Summary
Regular physical activity influences epigenetic modifications, impacting gene expression and histone proteins. Exercise aids in preventing age-related diseases and certain cancers by modulating these epigenetic factors.
Area of Science:
- Epigenetics and Molecular Biology
- Exercise Physiology
- Preventive Medicine
Background:
- Physical activity is a key epigenetic modifier.
- Epigenetic changes influence gene expression and cellular processes.
- Aging is associated with increased oxidative stress and disease risk.
Purpose of the Study:
- To investigate the effects of physical activity on histone proteins and gene expression.
- To explore how exercise impacts the prevention of age-related diseases and cancer.
- To understand the role of epigenetic modifications in these processes.
Main Methods:
- Review of existing scientific literature on physical activity and epigenetics.
- Analysis of studies examining histone protein expression changes.
- Examination of research on exercise and disease prevention mechanisms.
Main Results:
- Regular exercise positively affects histone protein expression.
- Physical activity can influence gene expression related to disease prevention.
- Exercise contributes to mitigating age-related cellular oxidation.
Conclusions:
- Regular physical activity and exercise induce beneficial epigenetic changes.
- These epigenetic modifications play a role in preventing cancer and age-related illnesses.
- Exercise is a viable strategy for managing oxidative stress and promoting healthy aging.
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