Effects of ethanol on negative phototaxis and motility in brown planarians (Dugesia tigrina)
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Updated: Feb 6, 2026

A Planarian Motility Assay to Gauge the Biomodulating Properties of Natural Products
Published on: May 30, 2020
1Department of Psychology, Massachusetts College of Liberal Arts, 375 Church Street, North Adams, MA, 01247, United States.
Abstract:
The behavioral effects of ethanol in brown planarians were studied in four experiments. In the first two experiments, acute administrations of ethanol increased travel time in a dose-dependent fashion in individual planarians moving away from a light source. Orderly results were obtained using both within-subject and between-group designs. In a third experiment, ethanol dose was arranged by time rather than concentration. Ethanol increased travel time overall, but variability between subjects was considerable. In a final experiment, ethanol administration reduced motility and altered movement patterns in planarians in an open-field test. These experiments demonstrated that negative phototaxis by planarians may exhibit sufficient stability to allow for experimental determinations of dose-response curves utilizing both within-subject and between-subject designs.
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