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Updated: Aug 13, 2026

Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay
06:29

Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay

Published on: March 1, 2011

Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

H Besedovsky, A del Rey, E Sorkin

    Science (New York, N.Y.)
    |August 8, 1986
    PubMed
    Summary

    Interleukin-1 (IL-1) stimulates the pituitary-adrenal axis, increasing glucocorticoid levels. This finding reveals a feedback loop where IL-1 signals the immune system to the brain, and glucocorticoids regulate the immune response.

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