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Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

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Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
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Coronary Artery Disease V: Interprofessional Care01:27

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Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
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Coronary Artery Disease III: Clinical Manifestations01:30

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Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

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Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
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Coronary Circulation01:21

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The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
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Related Experiment Video

Updated: Feb 6, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
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Coronary Artery Vasospasm.

Jae Kwan Song1

  • 1Department of Cardiology, Asan Medical Center Heart Institute, University of Ulsan College of Medicine, Seoul, Korea. jksong@amc.seoul.kr.

Korean Circulation Journal
|August 28, 2018
PubMed
Summary
This summary is machine-generated.

Coronary artery vasospasm (CVS) causes myocardial ischemia and various heart conditions. Prompt diagnosis via spasm provocation tests is crucial for effective patient management.

Keywords:
Coronary artery vasospasm

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Area of Science:

  • Cardiology
  • Vascular Medicine
  • Ischemic Heart Disease

Background:

  • Coronary artery vasospasm (CVS) is a significant cause of myocardial ischemia.
  • CVS can manifest as silent ischemia, angina, acute coronary syndrome, myocardial infarction, or sudden cardiac death.
  • Understanding CVS pathogenesis, clinical features, diagnosis, and treatment is vital.

Purpose of the Study:

  • To summarize the pathogenesis, clinical features, diagnosis, and treatment of CVS.
  • To emphasize the importance of pharmacological spasm provocation tests for accurate CVS diagnosis.
  • To advocate for increased utilization of provocative testing during coronary angiography.

Main Methods:

  • Review of literature on Coronary Artery Vasospasm (CVS).
  • Emphasis on diagnostic methods including pharmacological spasm provocation tests.
  • Integration of coronary angiography and echocardiographic monitoring for CVS detection.

Main Results:

  • Pharmacological spasm provocation tests are essential for diagnosing CVS.
  • Underutilization of these tests during coronary angiography is not justified.
  • Physician vigilance is necessary for objective CVS documentation.

Conclusions:

  • Accurate diagnosis of CVS is critical for managing ischemic heart disease.
  • Pharmacological provocation tests are underutilized but necessary.
  • Objective documentation of CVS guides appropriate patient management.