Related Experiment Video

Updated: Feb 6, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

22.6K

A case of prenatal chronic intestinal pseudo-obstruction associated with Leigh syndrome

Toshiyuki Itai1, Hiroshi Ishikawa1, Kenji Kurosawa2

  • 1Department of Obstetrics and Gynecology Kanagawa Children's Medical Center Yokohama Kanagawa Japan.

Clinical Case Reports
|August 28, 2018
PubMed

Insights

Chronic intestinal pseudo-obstruction (CIPO) is a key indicator of mitochondrial disorders. This study reports the first fetal case of bowel dilation linked to Leigh syndrome, suggesting CIPO consideration for mild fetal bowel dilation.

Area of Science:

  • Genetics
  • Pediatrics
  • Neurology

Background:

  • Chronic intestinal pseudo-obstruction (CIPO) is a significant clinical manifestation associated with mitochondrial disorders.
  • Mitochondrial disorders can present with a wide range of symptoms, impacting multiple organ systems.

Keywords:
Leigh syndromebowel dilationchronic intestinal pseudo‐obstructionprenatal diagnosis

More Related Videos

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms02:34

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

1.9K
An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation06:28

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

374

Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.6K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.6K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.8K
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.2K
Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
5.2K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.7K