Related Experiment Video
Updated: Feb 6, 2026

Construction and Testing of Coin Cells of Lithium Ion Batteries
Published on: August 2, 2012
Differential response to lithium between melancholic and non-melancholic unipolar depression
Marina P Valerio1, Diego J Martino2
1National Council of Scientific and Technical Research (CONICET), Buenos Aires, Argentina; Psychiatric Emergencies Hospital Torcuato de Alvear, Buenos Aires, Argentina; ÁREA, Assistance and Research in Affective Disorders, Buenos Aires, Argentina.
Abstract:
The purpose of this report was to review the evidence regarding the differential response to lithium treatment between patients with unipolar melancholic and non-melancholic depression. Three studies suggest that the prophylactic effect of lithium in maintenance treatment may be greater in melancholic depression. Another study reported that melancholic symptoms, such as weight loss and psychomotor disturbances, predict a better response to lithium augmentation. These preliminary data suggest that the response to lithium may be greater in melancholic than in non-melancholic depression, which could be the focus of further research.
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Depression: Overview
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

