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Affect plays a crucial role in shaping interpersonal evaluations and perceptions. Emotions influence how individuals judge and respond to others, often determining whether interactions are viewed positively or negatively. This effect can manifest directly through interactions with the person in question or indirectly via associations with unrelated emotional experiences.Direct Effects of Affect on AttractionAffect directly influences interpersonal attraction when a person’s behavior...
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Related Experiment Video

Updated: Feb 6, 2026

Evaluating Postural Control and Lower-extremity Muscle Activation in Individuals with Chronic Ankle Instability
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Affective instability in those with and without mental disorders: A case control study.

Steven Marwaha1, Charlotte Price2, Jan Scott3

  • 1Mental Health and Wellbeing, Division of Health Sciences, University of Warwick, CV47AL, UK; Institute for Mental Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Journal of Affective Disorders
|August 28, 2018
PubMed
Summary

Individuals with mental disorders exhibit greater affective lability and reduced affect control compared to controls. Affective instability, particularly affect lability, negatively impacts daily functioning, suggesting it as a key intervention target.

Keywords:
Affective instabilityBipolar disorderDepressionFunctioningMood instability

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Mental Health Research

Background:

  • Affective instability (AI) is a transdiagnostic feature linked to suicidality and healthcare utilization.
  • Limited research has compared AI across different psychiatric diagnoses and with healthy controls.
  • Understanding AI's components and their relationship with functioning is crucial for targeted interventions.

Purpose of the Study:

  • To investigate differences in AI between psychiatric patients and controls.
  • To compare AI across diagnoses including borderline personality disorder, bipolar disorder, major depression, and psychosis.
  • To examine the correlation between AI components and their association with functional impairment.

Main Methods:

  • A comparative study involving 69 psychiatric cases and 25 primary care controls.
  • Assessment of affective lability (ALS), affective intensity (AIM), and affective control (ACS).
  • Inclusion of mood fluctuation rate and WHO Disability Assessment Schedule (WHO-DAS) for functioning assessment.

Main Results:

  • Significant differences in affective lability and affective control were observed between clinical cases and controls, and across diagnostic groups.
  • No significant differences were found in affective intensity or mood fluctuation rate between groups.
  • Affective lability (ALS score) and medication count were independently associated with impaired daily functioning.

Conclusions:

  • Individuals with mental disorders exhibit higher affective lability and lower affective control than controls.
  • Affective intensity may not be a distinguishing feature of abnormal affective experience.
  • Affective instability, specifically affective lability, significantly impairs functioning and represents a potential clinical intervention target.