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State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

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Features of serial cranial ultrasound detected neuropathology in very preterm infants

A Petrova1, M Karatas2, R Mehta1

  • 1Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Journal of Neonatal-Perinatal Medicine
|August 29, 2018
PubMed

Insights

Changes in cranial ultrasound findings in very preterm infants are linked to neonatal conditions. Initial findings and morbidities help predict brain lesions by one month of age, aiding clinical management.

Area of Science:

  • Neonatal neurology
  • Pediatric imaging
  • Perinatal medicine

Background:

  • Cranial ultrasound (CUS) is crucial for monitoring brain development in preterm infants.
  • Understanding changes in CUS findings is essential for managing very preterm neonates.

Purpose of the Study:

  • To identify patterns and factors associated with changes in cranial ultrasound findings.
  • To analyze alterations in CUS detected findings in infants born at or before 28 weeks of gestation.

Main Methods:

  • Comparison of CUS readings from the first week and 4-5 weeks of life.
  • Classification of CUS findings as unchanged, worsening, or improved.
  • Statistical analysis including logistic regression and kappa statistics.

Main Results:

  • 82.3% of infants had unchanged CUS findings, 10.0% showed worsening, and 7.7% improved.
  • Moderate agreement (k=0.62) was observed between initial and later CUS scans.
  • Worsening CUS findings correlated with neonatal morbidities, particularly with initial intraventricular hemorrhage (IVH) grades.

Conclusions:

  • Initial CUS findings and neonatal morbidities predict brain lesions in very preterm infants by one month.
  • This predictive capability can inform clinical management strategies for these vulnerable infants.
Abstract

Keywords:
Neuropathologyserial cranial ultrasoundvery preterm infants

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