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Recurrent chikungunya retinitis.

Silvia Olivia Salceanu¹, Vasant Raman¹

¹University hospitals of Plymouth, Royal Eye Infirmary, Derriford, Plymouth, UK.

BMJ Case Reports

|August 29, 2018

Summary

Chikungunya virus infection can cause delayed eye inflammation, even nearly a year after initial exposure. Early corticosteroid treatment is crucial for favorable visual outcomes in ocular chikungunya cases.

Area of Science:

Ophthalmology
Infectious Diseases
Virology

Background:

Chikungunya virus (CHIKV) is a mosquito-borne illness causing fever, rash, and severe joint pain.
Ocular manifestations of chikungunya are diverse, including conjunctivitis and retinal detachment.
Prompt corticosteroid treatment typically improves outcomes in ocular chikungunya.

Observation:

A patient returning from Mexico presented with chikungunya infection confirmed by Reverse Transcriptase-PCR.
This case highlights a significant delay of nearly one year between CHIKV infection and the onset of ocular symptoms.
The patient experienced recurrent ocular inflammation, both episodes responding to systemic corticosteroid therapy.

Findings:

Delayed-onset ocular inflammation is a potential complication of chikungunya virus infection.

Keywords:

eye infections retina

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Systemic corticosteroid therapy was effective in managing both the initial and recurrent episodes of ocular inflammation.

The patient achieved a favorable visual outcome despite the delayed presentation.

Implications:

Ophthalmologists should consider chikungunya virus infection in patients with unexplained uveitis or other ocular inflammatory conditions, especially those with a travel history to endemic areas.
The prolonged incubation period for ocular symptoms necessitates sustained vigilance and monitoring in affected individuals.
Further research is warranted to understand the pathogenesis of delayed ocular manifestations and optimize treatment strategies for chikungunya-related eye disease.