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Infant growth outcomes from birth to 12 months of age: findings from the Delta Healthy Sprouts randomized comparative
J L Thomson1, M H Goodman1, L M Tussing-Humphreys2
1United States Department of Agriculture Agricultural Research Service Stoneville MS USA.
Insights
An enhanced lifestyle intervention did not prevent infant overweight or rapid weight gain in a maternal and child health project. This study highlights the need for more effective strategies to combat early childhood obesity.
Area of Science:
- Public Health
- Maternal and Child Health
- Obesity Prevention
Background:
- Childhood obesity is a growing public health concern.
- Early life interventions targeting maternal and infant health are crucial for prevention.
- Lifestyle modification programs during pregnancy and early infancy show potential.
Purpose of the Study:
- To evaluate the impact of a multicomponent lifestyle intervention on infant growth outcomes.
- To compare infant growth trajectories between an enhanced intervention group and a control group.
- To determine if a home visiting project improved infant weight status.
Main Methods:
- Recruitment of pregnant women in the lower Mississippi Delta.
- Randomized controlled trial with experimental and control arms over 18 months.
- Analysis of infant growth outcomes using Kaplan-Meier survival curves and log-rank tests.
Main Results:
- High retention rates in both experimental (88%) and control (83%) groups.
- Approximately 75% of infants in both arms were overweight by 12 months.
- No significant differences in time to overweight classification or rapid weight gain between groups.
Conclusions:
- The enhanced lifestyle intervention was not effective in improving infant growth outcomes.
- Diet and physical activity components did not alter infant growth compared to standard education.
- Further research is needed to develop effective early childhood obesity prevention strategies.
Objective:
Multicomponent lifestyle modification interventions designed for gestational and early postnatal periods may be key to preventing obesity in children. The primary objective of the study was to determine if infant growth outcomes differed between treatment arms of an 18-month, maternal, infant and early childhood home visiting project.
Methods:
Pregnant women at least 18 years of age, less than 19 weeks pregnant and residing in a lower Mississippi Delta county were recruited between March 2013 and December 2014. Postnatal data were collected from 24 experimental and 30 control participants between September 2013 and May 2016. Infant growth outcomes were modelled as time-to-event data using Kaplan-Meier survival curves with log-rank tests to determine if survival curves differed between treatment arms.
Results:
Retention rates for the experimental and control arms were 88% (21/24) and 83% (25/30), respectively. Approximately three-fourths of infants in both treatment arms were classified as overweight and experienced rapid weight gain during the first 12 months of life. No differences between median times neither to classification as overweight (3-4 months) nor to experiencing rapid weight gain (6-7 months) were observed between treatment arms.
Conclusions:
As compared with a standard educational (control) curriculum, an educational curriculum enhanced with diet and physical activity components was not effective at improving infant growth outcomes.
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