Related Experiment Video
Updated: Feb 6, 2026
03:27
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
1.3K
Is Nighttime Really Not the Right Time for a Laparoscopic Cholecystectomy?
Anna C M Geraedts1, Meindert N Sosef1, Jan Willem M Greve1
1Department of Surgery, Zuyderland Medical Centre, Heerlen & Sittard, Netherlands.
Canadian Journal of Gastroenterology & Hepatology
|August 29, 2018
Summary
Out-of-hours laparoscopic cholecystectomy is not an independent risk factor for complications. Emergency surgery and conversion to open procedures increase risks, but time of day alone is not a contraindication.
Area of Science:
- Surgical Outcomes
- Gastrointestinal Surgery
- Patient Safety
Background:
- The timing of laparoscopic cholecystectomy, particularly out-of-hours procedures, and its effect on patient outcomes remain debated.
- Understanding factors influencing postoperative complications is crucial for optimizing surgical care.
Purpose of the Study:
- To investigate the association between out-of-hours laparoscopic cholecystectomy and the risk of postoperative complications within 90 days.
- To identify independent risk factors for morbidity following cholecystectomy.
Main Methods:
- A prospective analysis of 1553 laparoscopic cholecystectomies performed between 2014 and 2016.
- Data collected included therapeutic, operative, and outcome variables, with out-of-hours defined as evenings, nights, weekends, and holidays.
Main Results:
- Out-of-hours procedures (9.3%) had a higher conversion rate to open surgery (9.7% vs 2.0%).
- Univariate analysis suggested an increased risk with out-of-hours procedures, but multivariate analysis found no independent association.
- Operation by surgical staff and conversion to laparotomy were independently associated with increased complications.
Conclusions:
- Out-of-hours laparoscopic cholecystectomy is not an independent risk factor for postoperative morbidity.
- Time of day should be considered a relative, not absolute, contraindication for cholecystectomy.
- Focusing on emergency status and surgical conversion is key to reducing complications.
Related Concept Videos
01:22Mean free path and Mean free time
5.2K
Consider the gas molecules in a cylinder. They move in a random motion as they collide with each other and change speed and direction. The average of all the path lengths between collisions is known as the "mean free path."
5.2K
01:19Mixing Time
481
The concept of mixing time is significant in producing a uniform concrete mix with the required strength. The mixing period starts once all components are in the mixer. Initially, the mixer is charged with 10% of the water, followed by the consistent addition of solids and then 80% of the water. The remaining water is added later, within the first quarter of the mixing period. The minimum mixing time varies according to the mixer's capacity; for example, mixers with up to 1 cubic yard...
481
01:22Generation Time
1.5K
Bacterial generation time, the period required for a bacterial population to double during its exponential growth phase, serves as a critical measure of microbial growth dynamics under optimal conditions. This parameter varies significantly across bacterial species and can be influenced by factors such as temperature, pH, and the availability of nutrients. For example, Escherichia coli can achieve a generation time of approximately 20 minutes, while Mycobacterium tuberculosis exhibits a much...
1.5K
01:14Time Course of Drug Effect
2.8K
The progression of a drug's impact can be analyzed by examining both the concentration-time course and the effect-time course. The concentration-time course is determined by the drug's half-life and is influenced by factors such as its pharmacokinetics, including absorption, distribution, metabolism, and elimination. The effect of the drug is often related to its concentration in the plasma and is calculated using the maximum drug effect and the plasma concentration that generates 50...
2.8K
01:12Setting Time of Cement
700
The setting time of cement refers to the process of cement paste transitioning from a plastic state to a solid state. This process is crucial in construction as it dictates the timeframe for concrete placement, compaction, and finishing. The onset of this solidification is termed the initial set, indicating when the paste becomes unworkable. The final set is when the paste has solidified completely, and further handling or manipulation can no longer affect its shape. The cement strength is...
700
01:08Timing and Consequences on Behavior
398
In operant conditioning, the timing of reinforcement is crucial. For animals like rats and cats, immediate reinforcement (within a few seconds) is much more effective than delayed reinforcement. For example, a food reward for a rat needs to follow within 30 seconds of pressing a bar to be effective.
Humans, however, can respond to delayed reinforcers. We often make decisions between immediate small rewards and delayed larger rewards. This ability to delay gratification is a significant...
Humans, however, can respond to delayed reinforcers. We often make decisions between immediate small rewards and delayed larger rewards. This ability to delay gratification is a significant...
398