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Related Experiment Videos

[Sandfly fever-a "neglected" disease].

B Stahn1, H Sudeck1, H Frickmann1

  • 1Fachbereich Tropenmedizin des Bundeswehrkrankenhauses Hamburg am Bernhard-Nocht Institut, Bernhard-Nocht Str. 74, 20359, Hamburg, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|August 29, 2018
PubMed
Summary

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Sandfly fever Sicilian virus (SFSV), also known as pappataci fever, caused a traveler's illness with fever, rash, and elevated liver enzymes. This case highlights the importance of considering phlebovirus infections in returning travelers.

Area of Science:

  • Tropical Medicine
  • Virology
  • Epidemiology

Background:

  • Sandfly fever, caused by phleboviruses, is transmitted by sandflies and prevalent in Mediterranean regions.
  • Clinical presentation can include fever, rash, and hepatitis, mimicking other febrile illnesses.
  • Differential diagnosis in travelers returning from endemic areas is crucial.

Observation:

  • A traveler returning from northern Cyprus presented with fever, rash, diarrhea, and elevated liver enzymes.
  • Exposure to biting insects, likely sandflies, was reported in the endemic area.
  • Clinical presentation suggested sandfly fever, prompting serological testing.

Findings:

  • Antibodies to sandfly fever Sicilian virus (SFSV) were detected, confirming the diagnosis of pappataci fever.
Keywords:
MediterraneanMeningitisPappataci feverPhlebovirusVector-borne diseases

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  • The patient's clinical course and antibody dynamics were consistent with SFSV infection.
  • Elevated transaminases and C-reactive protein indicated systemic inflammation and liver involvement.

    • Implications:

    • This case highlights the importance of considering phlebovirus infections, such as SFSV, in travelers presenting with hepatitis and rash.
    • Prompt recognition and diagnosis of pappataci fever are essential for managing potential complications.
    • Increased awareness among clinicians can improve the diagnosis of imported viral diseases in returning travelers and refugees.