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Updated: Feb 6, 2026

Three-Dimensional Preoperative Virtual Planning in Derotational Proximal Femoral Osteotomy
Published on: February 17, 2023
A novel approach to skull-base and orbital osteotomies through virtual planning and navigation
Leonardo Franz1, Miriam Isola1,2, Daniele Bagatto3
1Department of Maxillofacial Surgery, Academic Hospital of Udine, Department of Medicine, University of Udine, Udine, Italy.
Objective:
Computer-assisted planning of osteotomy lines, coupled with navigation-guided performance of planned osteotomies, is a highly innovative approach to skull-base and orbital surgery. The aim of this pilot study is to provide an assessment of the accuracy of this novel approach in guiding the correct positioning of osteotomy lines in frontal, temporal, and orbital regions, defining the agreement between the spatial position of the planned and performed osteotomies.
Methods:
Fifteen patients with orbital, frontal sinus, and lateral skull-base diseases underwent virtual surgical planning. Osteotomies to access the orbit, frontal sinus, and lateral skull base were planned on computer tomography-based three-dimensional models. The planned osteotomies were reproduced on the operating field using a navigation system. The positions of the performed and planned osteotomies were compared. The results were described as the mean positional difference between planned and performed osteotomies and as Lin's concordance coefficient, and Bland-Altman limits of agreement were also defined.
Results:
The overall mean difference was 0.719 mm (95% confidence interval [CI]: 0.472 to 0.965 mm). Overall, Lin's concordance coefficient was 0.997 (95% CI: 0.996 to 0.998), and overall Bland-Altman limits of agreement ranged from -1.407 to 2.844 mm. The smallest mean difference (0.587 mm, 95% CI: 0.244 to 0.931 mm) was calculated in the orbit group, whereas the highest mean difference (0.904 mm, 95% CI: 0.428 to 1.379 mm) was described in the lateral skull-base group.
Conclusion:
This study's results support the use of this novel planning and navigation protocol for guiding osteotomy in anterior and lateral skull-base surgery, providing a clinical validation of this technique.
Level Of Evidence:
4 Laryngoscope, 00:1-9, 2018 Laryngoscope, 129:823-831, 2019.
Insights
This pilot study demonstrates that computer-assisted planning and navigation accurately guide osteotomy placement in skull-base and orbital surgery. The novel technique shows high agreement between planned and performed osteotomies, supporting its clinical use.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Medical Technology
Background:
- Computer-assisted planning and navigation represent an innovative approach to skull-base and orbital surgery.
- Accurate osteotomy placement is crucial for successful surgical outcomes in these complex regions.
Purpose of the Study:
- To assess the accuracy of computer-assisted planning and navigation in guiding osteotomy lines in frontal, temporal, and orbital regions.
- To define the spatial agreement between planned and performed osteotomies in skull-base surgery.
Main Methods:
- Fifteen patients underwent virtual surgical planning using 3D models derived from CT scans.
- Osteotomies were planned and then reproduced in the operating field using a navigation system.
- Comparison of planned and performed osteotomies was conducted using mean positional difference, Lin's concordance coefficient, and Bland-Altman limits of agreement.
Main Results:
- The overall mean difference between planned and performed osteotomies was 0.719 mm.
- High concordance was observed, with Lin's coefficient at 0.997.
- The smallest mean difference was in the orbit group (0.587 mm), and the largest in the lateral skull-base group (0.904 mm).
Conclusions:
- The study supports the use of this novel planning and navigation protocol for osteotomy guidance in anterior and lateral skull-base surgery.
- This technique provides clinical validation for computer-assisted approaches in complex craniofacial procedures.
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