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Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
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[Preface for special issue on antimicrobial resistance].

Yongfei Hu1, Baoli Zhu2,3

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Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
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Antimicrobial resistance is a growing global threat due to heavy antibiotic use. This review covers clinical, environmental, and mechanistic aspects, offering strategies for prevention and control.

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Area of Science:

  • Microbiology
  • Public Health
  • Environmental Science

Background:

  • Antibiotics are vital for treating bacterial infections.
  • Extensive antibiotic use has accelerated the spread of antimicrobial resistance (AMR).
  • AMR poses significant medical, social, and economic challenges, impacting public health and food safety.

Purpose of the Study:

  • To review recent advancements in antimicrobial resistance research.
  • To provide a comprehensive overview of AMR challenges and solutions.
  • To identify future research directions and control strategies for AMR.

Main Methods:

  • Literature review and synthesis of current research on antimicrobial resistance.
  • Discussion of findings across clinical, epidemiological, animal, and environmental domains.
  • Analysis of drug resistance mechanisms and antimicrobial drug development.

Main Results:

  • The review highlights the multifaceted nature of AMR, spanning clinical and environmental contexts.
  • It examines various mechanisms contributing to drug resistance.
  • Progress in antimicrobial drug development and control strategies is discussed.

Conclusions:

  • Antimicrobial resistance requires a multi-pronged approach involving clinical, environmental, and developmental strategies.
  • Understanding resistance mechanisms is crucial for effective prevention and control.
  • Continued research and global cooperation are essential to combat AMR.