Related Experiment Video

Updated: Feb 6, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

1.0K

Management of Erectile Dysfunction: An Under-Recognition of Hypertension

Gokhan Koroglu1, Ecem Kaya-Sezginer1, Didem Yilmaz-Oral1,2

  • 1Department of Biochemistry and Pharmacology, Faculty of Pharmacy, Ankara University, Ankara, Turkey.

Current Pharmaceutical Design
|August 29, 2018
PubMed

Insights

Hypertension can cause erectile dysfunction (ED) through high blood pressure or medication side effects. Understanding these links may lead to new treatments for improving men's quality of life.

Area of Science:

  • Cardiovascular Medicine
  • Urology
  • Pharmacology

Background:

  • Erectile dysfunction (ED) impacts 30 million US men, reducing quality of life.
  • Thirty percent of men with hypertension experience ED.

Purpose of the Study:

  • To review the relationship between hypertension and ED.
  • To explore hypertension-induced ED mechanisms.
  • To examine the effects of antihypertensive medications on ED.

Main Methods:

  • Literature search of PubMed records from January 2000 to June 2018.

Main Results:

  • Hypertension can directly cause ED or result from antihypertensive treatments.
  • Endothelial dysfunction is a shared mechanism in both hypertension and ED.
  • Phosphodiesterase (PDE)-5 inhibitors for ED may improve blood pressure.

Conclusions:

  • Understanding shared mechanisms is crucial for novel therapeutic strategies.
  • Research into antihypertensive drugs impacting ED can improve patient quality of life.
Abstract

Keywords:
Antihypertensive treatmentendothelial dysfunctionerectile dysfunctionhigh blood pressurehypertensionphosphodiesterase-5 inhibitors.

More Related Videos

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.9K
Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents08:03

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents

Published on: June 6, 2018

15.1K

Related Concept Videos

Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
445
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
902
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
963
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
4.3K
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
659
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
436