Low Grade Chondrosarcoma - Epidemiology, Diagnosis, Treatment

The article describes epidemiology, clinical features and treatment strategy of chondrosarcoma with special regard to diagnostic and therapeutic difficulties in low grade chondrosarcomas. Chondrosarcomas account for 3.5-9% of primary bone tumors and approximately 30% of primary bone malignancies. They occur in the 4th to 7th decade of life, slightly more commonly in men. The most common locations are the pelvis, ribs, proximal femur and proximal humerus. Gradually increasing pain is the most common presenting symptom. Diagnosis must be based on clinical, radiological (conventional radiology, computed tomography, magnetic resonance imaging) and histopathological features. Treatment of the tumor is based on complete removal according to the principles of oncological asepsis. Lung metastases may develop and are associated with a markedly poorer prognosis.