Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adhesion01:14

Adhesion

44.5K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
44.5K
Silica Gel Column Chromatography: Overview01:10

Silica Gel Column Chromatography: Overview

3.6K
Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
3.6K
Cell Adhesion in Plants01:14

Cell Adhesion in Plants

3.4K
Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
3.4K
Modified Boxplots00:57

Modified Boxplots

11.2K
A standard box and whisker plot informs us about the spread of the data in a given sample. One can identify the minimum value, maximum value, first quartile value, second quartile or median value, and third quartile.
However, the box plot does not tell the reader about outliers - values that lie far from the center of the data. We can modify the standard box and whisker plot to identify the outliers and visualize the actual spread of the data in a sample.
Initially, we calculate the adjusted...
11.2K
Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

4.4K
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
4.4K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

3.6K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The influence of posture on the three-dimensional mandibular position relative to the maxillary coordinate system in centric relation.

BMC oral health·2026
Same author

Multifaceted influence of surface treatments on resin-matrix ceramics: Cytocompatibility, mechanical properties, and adhesion strategies.

Journal of dentistry·2026
Same author

Expert Consensus on Clinical Application for Digital Full-contour High-translucent/Ultra-translucent Zirconia Restorations.

The Chinese journal of dental research·2026
Same author

Effect of physical activity on pulmonary function and quality of life in asthma patients: a systematic review and meta-analysis.

Frontiers in medicine·2026
Same author

The impact of ward nighttime noise management under the enhanced recovery after surgery protocol on postoperative sleep quality and mental health in patients with lower extremity fractures: A retrospective, non-randomized, historically controlled study.

Pakistan journal of medical sciences·2026
Same author

Comparative mechanical analysis of collagen membranes derived from different tissues in an in vitro model simulating membrane-stabilized horizontal GBR.

BMC oral health·2026

Related Experiment Video

Updated: Feb 6, 2026

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica
11:02

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica

Published on: July 9, 2015

10.6K

Chlorhexidine-encapsulated mesoporous silica-modified dentin adhesive.

Huiyi Yan1, Shilei Wang2, Lin Han3

  • 1The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory for Oral Biomedical Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

Journal of Dentistry
|August 29, 2018
PubMed
Summary

Chlorhexidine-encapsulated mesoporous silica (CHX@pMSN) modified dental adhesives effectively inhibit Streptococcus mutans biofilm growth. The 5% CHX@pMSN modification balances bond strength and durability, potentially extending restoration longevity.

Keywords:
AdhesiveAntibacterialChlorhexidineDentinMesoporous silica

More Related Videos

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
13:00

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Published on: April 17, 2012

14.0K
Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity
11:06

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Published on: March 1, 2016

10.8K

Related Experiment Videos

Last Updated: Feb 6, 2026

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica
11:02

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica

Published on: July 9, 2015

10.6K
Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
13:00

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery

Published on: April 17, 2012

14.0K
Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity
11:06

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Published on: March 1, 2016

10.8K

Area of Science:

  • Dental Materials Science
  • Biomaterials Engineering
  • Nanotechnology in Dentistry

Background:

  • Dental caries remains a significant global health issue, often requiring adhesive restorations.
  • Secondary caries and biofilm formation at the adhesive-dentin interface are major causes of restoration failure.
  • Developing dental adhesives with inherent antibacterial properties is crucial for improving long-term clinical outcomes.

Purpose of the Study:

  • To investigate the feasibility of using chlorhexidine-encapsulated mesoporous silica nanoparticles (CHX@pMSN) to enhance a commercial dental adhesive.
  • To evaluate the impact of CHX@pMSN incorporation on the physicochemical properties and antibacterial efficacy of the adhesive-dentin interface.
  • To determine the optimal concentration of CHX@pMSN for balancing antibacterial activity and adhesive bond strength.

Main Methods:

  • Commercial dental adhesive was modified with CHX@pMSN at varying mass fractions (0, 1, 5, 10 wt.%).
  • Antibacterial activity against Streptococcus mutans (S. mutans) biofilm was assessed using MTT and CLSM assays.
  • Physicochemical properties including degree of conversion, morphology, microtensile bond strength (MTBS), and nanoleakage were evaluated.
  • Bonded specimens were subjected to collagenase aging to assess long-term durability.

Main Results:

  • CHX@pMSN-doped adhesives demonstrated significant inhibition of S. mutans biofilm growth with continuous chlorhexidine release.
  • Incorporation of 1% and 5% CHX@pMSN did not compromise immediate bond strength (P > 0.05).
  • The 5% CHX@pMSN group exhibited well-preserved bond strength after one month of collagenase aging and comparable nanoleakage to the control group.

Conclusions:

  • The 5% CHX@pMSN-modified dental adhesive effectively inhibits S. mutans biofilm while maintaining immediate bond strength and long-term durability.
  • This modified adhesive presents a promising strategy for enhancing the longevity of dental adhesive restorations.
  • CHX@pMSN represents a viable additive for developing therapeutic dental adhesives with improved clinical performance.