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Validating the Geriatric Depression Scale with proxy-based data: A case-control psychological autopsy study in rural
Lu Niu1, Cunxian Jia2, Zhenyu Ma3
1The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), 36 Mingxin Road, Liwan District, Guangzhou 510370, China.
The Geriatric Depression Scale (GDS-30 and GDS-15) is valid for assessing depression severity in rural Chinese suicide cases using proxy data. The GDS-15 is a suitable alternative to the GDS-30 in this context.
Area of Science:
- Gerontology
- Psychiatry
- Epidemiology
Background:
- The Geriatric Depression Scale (GDS) is commonly used for late-life depression.
- Validation of GDS in psychological autopsy research, particularly with proxy data in rural China, is lacking.
Purpose of the Study:
- To assess the validity of the GDS-30 and GDS-15 using proxy-based data in rural China.
- To establish optimal cut-off values for these scales in psychological autopsy research.
Main Methods:
- Psychological autopsy was conducted on 242 suicide cases and 242 matched living controls.
- Subject-proxy concordance was assessed for GDS-30 and GDS-15.
Main Results:
- Fair subject-proxy concordance was observed for both GDS-30 (ICC=0.590) and GDS-15 (ICC=0.539).
- Suicide cases exhibited higher depression scores than controls.
- GDS-30 and GDS-15 demonstrated good internal consistency and correlated with hopelessness, loneliness, and quality of life.
Conclusions:
- The GDS-30 and GDS-15 are valid for measuring depression severity, not for screening major depression, in rural Chinese psychological autopsy studies.
- The GDS-15 is a viable substitute for the GDS-30 in this research setting.
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