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Updated: Feb 6, 2026

A Mouse Model for Laser-induced Choroidal Neovascularization
Published on: December 27, 2015
Etiologies and Characteristics of Choroidal Neovascularization in Young Chinese Patients
Bing Liu1, Xiongze Zhang1, Yuting Peng1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Purpose:
To investigate the etiologies and characteristics of choroidal neovascularization (CNV) in young Chinese patients.
Methods:
A retrospective review of young Chinese patients (< 50 years of age) with CNV from January 2010 to June 2016 was performed.
Results:
Of the 501 patients (537 eyes) with CNV, 58.7% were female, and 7.2% had bilateral CNV. The mean age was 35 years. The etiologies were idiopathic CNV (ICNV, 43.9%), pathologic myopia (PM, 21.9%), punctate inner choroidopathy (PIC, 17.4%), polypoidal choroidal vasculopathy (4.4%), multifocal choroiditis with panuveitis (3.6%), and other disorders (8.8%). Five hundred and six CNVs (94.2%) showed a predominantly classic CNV composition on fundus fluorescein angiography (FFA) and 316 CNVs (96.6%) were type 2 CNV on optical coherence tomography (OCT).
Conclusion:
The etiologies of CNV in young Chinese patients were diverse, and ICNV, PM, and PIC were the three most common etiologies. Most CNVs were classic on FFA and type 2 on OCT.
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