Related Experiment Video

Updated: Feb 6, 2026

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.6K

Probiotics for management of infantile colic: a systematic review of randomized controlled trials

Radoslaw Dryl1, Hanna Szajewska1

  • 1Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland.

Archives of Medical Science : AMS
|August 30, 2018
PubMed

Insights

Probiotics, particularly Lactobacillus reuteri DSM 17938, may help manage infantile colic by reducing crying times, especially in breastfed infants. Further research is needed for other probiotic strains.

Area of Science:

  • Pediatric Gastroenterology
  • Microbiome Research

Background:

  • Infantile colic is a prevalent pediatric condition with unknown etiology and limited treatment options.
  • Probiotics are being investigated for their potential benefits in managing infantile colic.

Purpose of the Study:

  • To systematically evaluate the effectiveness of probiotic supplementation in infantile colic management.
  • To assess treatment success and crying duration as outcome measures.

Main Methods:

  • A systematic review of randomized controlled trials (RCTs) was conducted.
  • Searched MEDLINE and Cochrane Library up to April 2016 for relevant studies.
  • Included RCTs comparing probiotics to placebo for infantile colic.

Main Results:

  • Seven RCTs involving 471 participants were analyzed.
  • Lactobacillus reuteri DSM 17938 significantly improved treatment success and reduced crying duration in exclusively breastfed infants.
  • Other probiotic strains showed limited evidence due to single-trial studies.

Conclusions:

  • Lactobacillus reuteri DSM 17938 is a potential probiotic option for infantile colic management.
  • Evidence for other probiotics in infantile colic is currently limited.
Abstract

Keywords:
childreninfantsmicrobiota

More Related Videos

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K
Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

2.9K

Related Concept Videos

Random and Systematic Errors01:20

Random and Systematic Errors

Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
15.1K
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.5K
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
424
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.8K