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Preparation of SNS CobaltII Pincer Model Complexes of Liver Alcohol Dehydrogenase
Published on: March 19, 2020
Efficient and selective hydrogenation of amides to alcohols and amines using a well-defined manganese-PNN pincer
Veronica Papa1, Jose R Cabrero-Antonino1, Elisabetta Alberico1,2
1Leibniz-Institut für Katalyse , e.V. Albert-Einstein Str. 29a , 18059 Rostock , Germany .
Abstract:
Novel well-defined NNP and PNP manganese pincer complexes have been synthetized and fully characterized. The catalyst Mn-2 containing an imidazolyaminolphosphino ligand shows high activity and selectivity in the hydrogenation of a wide range of secondary and tertiary amides to the corresponding alcohols and amines, under relatively mild conditions. For the first time, more challenging substrates like primary aromatic amides including an actual herbicide can also be hydrogenated using this earth-abundant metal-based pincer catalyst.
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