Related Experiment Video
Updated: Feb 6, 2026

Visualization and Analysis of Pharyngeal Arch Arteries using Whole-mount Immunohistochemistry and 3D Reconstruction
Published on: March 31, 2020
Zone zero hybrid arch exclusion versus open total arch replacement
Ourania Preventza1,2, Corinne W Tan2, Vicente Orozco-Sevilla2
1Department of Cardiovascular Surgery, Texas Heart Institute, Houston, TX, USA.
Abstract:
Open total aortic arch replacement is one of the most technically demanding operations in cardiothoracic surgery, requiring operator expertise and intraoperative and postoperative teamwork. Despite current advancements in the field of open aortic surgery with regard to intraoperative brain protection and postoperative care, the morbidity and mortality associated with open total arch operations varies. Endovascular and hybrid procedures involving the use of zone 0 as a landing zone allow fair comparison between open total arch and hybrid operations. Hybrid procedures involving all of the other landing zones [1-4] should not be compared with open total arch replacement, as the extent of the pathology is different.
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