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Scanning electron microscopy of granuloma annulare
Hiram Larangeira de Almeida1,2, Eduardo de Barros Coelho Bicca3, Mariani Magnus de Andrade4
1Department of Dermatology, Universidade Federal de Pelotas, Pelotas (RS), Brazil.
Abstract:
Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granular mucin deposition were observed. Round cells corresponding to lymphocytes were identified. Bigger oval cells, corresponding to isolated or palisading histiocytes were also found. The ultrastructural aspects overlap with light microscopy and contribute to its iconographic documentation.
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