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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Case for diagnosis. Linear Darier's disease
Fernanda Del Pintor Bidoia1, Bruna Martini Massanares1, Eduardo Vinicius Mendes Roncada1
1Dermatology Service, Hospital Regional de Presidente Prudente, Universidade do Oeste Paulista, Presidente Prudente (SP), Brazil.
Anais Brasileiros De Dermatologia
|August 30, 2018
Summary
This case report details a rare linear manifestation of Darier's disease in a 60-year-old male. The diagnosis was challenging due to the unusual presentation along Blaschko's lines.
Area of Science:
- Dermatology
- Medical Genetics
Background:
- Darier\'s disease is a rare autosomal dominant genodermatosis.
- Typical presentations involve greasy, hyperkeratotic plaques.
- Linear Darier\'s disease is an extremely rare variant.
Observation:
- A 60-year-old male presented with a 6-year history of skin lesions.
- Lesions were brown to red papules and plaques with hyperkeratosis.
- The distribution followed Blaschko\'s lines on the abdomen.
Findings:
- The clinical presentation mimicked other dermatoses, delaying diagnosis.
- Dermatological workup and biopsy were crucial for confirming the diagnosis.
- Histopathology revealed characteristic features of Darier\'s disease.
Implications:
- Highlights the importance of considering rare variants in dermatological diagnosis.
- Emphasizes the diagnostic utility of biopsy in challenging cases.
- Contributes to the limited literature on linear Darier\'s disease.
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