Related Experiment Video
Updated: Feb 6, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
SCREENING TEST TO DETECT RECENT TOXOPLASMA GONDII INFECTIONS IN PREGNANT WOMEN
Abstract:
The differentiation between acute and latent forms of Toxoplasma gondii (T gondii) infection is still considered as a complicated issue. This study elucidated the establishment of a method that can detect most, if not all, of the recent infections with T gondii through detecting both the immunological and genetic markers. The study included cases' group (G1): 30 pregnant women considered to be a high-risk group (with history of abnormal pregnancy outcomes), and the controls (G2) were 20 apparently healthy women cross matched in ages but with a history of normal pregnancy. The two groups were subjected to PCR and immunoblotting in the diagnosis of T. gondii infection compared to the routinely used assays (Rapid toxo IgM by immunochromatog- raphy & ELISA IgM). The results showed that of 30 pregnant women (Gi) 3(10%) were positive by Rapid Toxo- IgM, 5(16.67%) by ELISA-IgM, 9(30%) by immunoblotting and 6(20%) by PCR.
Related Concept Videos
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Stages of Infection
Defense Mechanism Against Infection
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
Sexually Transmitted Infections
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

