Related Experiment Video
Updated: Feb 6, 2026

A Structured Approach to Extubation in Mechanically Ventilated Rats
Published on: July 18, 2025
Incidence of Immediate Extubation After Pediatric Cardiac Surgery and Predictors for Reintubation
Takeshi Shinkawa1, Xinyu Tang2, Jeffrey M Gossett2
11 Division of Pediatric and Congenital Cardiothoracic Surgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Insights
Immediate extubation after pediatric cardiac surgery is feasible in most cases. Higher inotropic scores predict the need for reintubation in single ventricle palliation patients.
Area of Science:
- Pediatric Cardiac Surgery
- Anesthesiology
- Critical Care Medicine
Background:
- Immediate tracheal extubation in the operating room (OR) is a goal in pediatric cardiac surgery.
- Predictors for reintubation after extubation require further investigation.
Purpose of the Study:
- To determine the incidence of immediate tracheal extubation in the OR after pediatric cardiac surgery.
- To identify predictors for subsequent reintubation in these patients.
Main Methods:
- Retrospective single-institutional study (2011-2016).
- Included patients undergoing cardiac operations with cardiopulmonary bypass.
- Excluded patients needing preoperative ventilation, open chest, or mechanical support.
- Subgroup analysis for stage II palliation to identify reintubation predictors.
Main Results:
- Immediate extubation occurred in 64.9% of 909 operations.
- Anesthesiologist, year, bypass time, and operation type influenced immediate extubation.
- Reintubation was less frequent with immediate extubation (6.1% vs 15.0%).
- In stage II palliation, younger age, lower blood gas values, and higher inotropic scores predicted reintubation.
Conclusions:
- Most pediatric cardiac surgery patients can undergo immediate OR extubation.
- Inotropic score is a significant predictor of reintubation in stage II palliation.
Objectives:
The objectives were to assess the incidence of immediate tracheal extubation in the operating room after pediatric cardiac surgery and to investigate predictors for subsequent reintubation.
Methods:
This is a single institutional retrospective study including all patients who had a cardiac operation with cardiopulmonary bypass from 2011 to 2016. Patients who required preoperative ventilator support, postoperative open chest, or mechanical support were excluded. Predictors for reintubation after immediate extubation were analyzed only for patients with stage II palliation for single ventricle physiology.
Results:
Nine hundred nine qualifying operations were identified. Immediate extubation was performed in 590 (64.9%) operations. A multivariable logistic regression model showed that the identities of anesthesiologist ( P = .0003), year of the operation performed ( P < .001), cardiopulmonary bypass time ( P < .001), and type of operations ( P < .001) were significantly associated with immediate extubation. Reintubation was significantly less frequent in patients with immediate extubation compared to those without (6.1% vs 15.0%; P < .001). A subgroup analysis for stage II palliation showed that reintubation after immediate extubation was significant for younger age (0.42 vs 0.54 years, P = .044), lower Po2/Fio2 and Po2 at the last blood gas analysis (66 vs 98 mm Hg, P = .032 and 39 vs 47 mm Hg, P = .008), and higher inotropic score (2 vs 0, P = .034). A multivariable logistic regression model showed that only inotropic score was significantly associated with reintubation ( P = .018).
Conclusions:
Immediate extubation in the operating room after pediatric cardiac surgery can be performed in most patients. Inotropic score is a predictor for reintubation in stage II palliation.
Related Concept Videos
Endotracheal Tube Extubation
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism

