Incidence of Immediate Extubation After Pediatric Cardiac Surgery and Predictors for Reintubation

Takeshi Shinkawa1, Xinyu Tang2, Jeffrey M Gossett2

  • 11 Division of Pediatric and Congenital Cardiothoracic Surgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Insights

Immediate extubation after pediatric cardiac surgery is feasible in most cases. Higher inotropic scores predict the need for reintubation in single ventricle palliation patients.

Area of Science:

  • Pediatric Cardiac Surgery
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Immediate tracheal extubation in the operating room (OR) is a goal in pediatric cardiac surgery.
  • Predictors for reintubation after extubation require further investigation.

Purpose of the Study:

  • To determine the incidence of immediate tracheal extubation in the OR after pediatric cardiac surgery.
  • To identify predictors for subsequent reintubation in these patients.

Main Methods:

  • Retrospective single-institutional study (2011-2016).
  • Included patients undergoing cardiac operations with cardiopulmonary bypass.
  • Excluded patients needing preoperative ventilation, open chest, or mechanical support.
  • Subgroup analysis for stage II palliation to identify reintubation predictors.

Main Results:

  • Immediate extubation occurred in 64.9% of 909 operations.
  • Anesthesiologist, year, bypass time, and operation type influenced immediate extubation.
  • Reintubation was less frequent with immediate extubation (6.1% vs 15.0%).
  • In stage II palliation, younger age, lower blood gas values, and higher inotropic scores predicted reintubation.

Conclusions:

  • Most pediatric cardiac surgery patients can undergo immediate OR extubation.
  • Inotropic score is a significant predictor of reintubation in stage II palliation.
Abstract

Related Concept Videos

Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
4.3K
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
266
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
314
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
236