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The Ex Vivo Colon Organ Culture and Its Use in Antimicrobial Host Defense Studies
Published on: February 13, 2017
Host defense peptides: An insight into the antimicrobial world
Shiva Gupta1, Gouri Bhatia2, Anamika Sharma1
1Department of Periodontology, Subharti Dental College, Meerut, India.
Abstract:
A serious challenge to antimicrobial therapies has emerged due to rapid increase in drug-resistant infections creating an urge for the development of alternative therapeutics. Antimicrobial peptides (AMPs) have gained importance because of their broad-spectrum antimicrobial activities and mediator-like functions linking innate and adaptive immune responses. The multidimensional properties of these peptides hold promising potentials as prophylactic and antimicrobial agents. This review discusses various AMPs and their role in combating microorganisms and infections along with its clinical implication.
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