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Updated: Feb 6, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
Published on: December 16, 2013
Aggregation of Rare Earth Coordination Complexes in Solution Studied by Paramagnetic and DOSY NMR
Adeline W J Poh1, Juan A Aguilar1, Alan M Kenwright1
1Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
Abstract:
The degree of aggregation of neutral, 9-coordinate rare earth coordination complexes has been shown to affect their ligand field, as revealed by diffusion-ordered NMR spectroscopy (DOSY-NMR) measurements on Y(III) complexes, paramagnetic NMR analyses of Yb and Tb analogues and emission spectral studies with the EuIII systems. In non-polar media a lipophilic tris-isopropyl complex, [Ln.L2 ] tends to aggregate in chloroform and dichloromethane giving rise to oligomers, whereas in acetic and trifluoroacetic acid the more polar parent complex, [Ln.L1 ], also aggregates, profoundly affecting the pseudocontact shift and the form of the Eu emission spectrum. Such behaviour has important implications in the design of responsive spectral probes.
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