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Related Concept Videos

Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
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Related Experiment Video

Updated: Feb 6, 2026

Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

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[AUTO-LUNG TRANSPLANTATION].

Masayuki Chida

    Nihon Geka Gakkai Zasshi
    |August 31, 2018
    PubMed
    Summary
    This summary is machine-generated.

    Extended resection with bronchovasculoplasty offers an alternative to pneumonectomy for lung cancer, preserving lung parenchyma. Bench surgery, a type of "auto-lung transplantation," facilitates lung graft excision with potential benefits.

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    Area of Science:

    • Thoracic Surgery
    • Surgical Oncology
    • Transplantation Immunology

    Background:

    • Locally advanced lung cancer often necessitates pneumonectomy, leading to significant lung function loss.
    • Extended resection techniques aim to preserve lung parenchyma and function.
    • Bronchovasculoplasty, a component of triple-plasty operations, is explored for lung preservation.

    Purpose of the Study:

    • To evaluate extended resection with bronchovasculoplasty as an alternative to pneumonectomy for lung cancer.
    • To describe the "auto-lung transplantation" technique, including in vivo transposition and ex vivo bench surgery.
    • To highlight the utility of bench surgery for lung graft excision and preservation.

    Main Methods:

    • Description of triple-plasty operations involving the bronchus, pulmonary artery, and pulmonary vein.
    • Comparison of in vivo "transposition" versus ex vivo "bench surgery" approaches.
    • Emphasis on lung graft irrigation with preservation solution to mitigate ischemic-reperfusion injury.

    Main Results:

    • Bench surgery facilitates easier lung graft excision compared to conventional methods.
    • The bench surgery approach does not appear to prolong operative time.
    • Bronchovasculoplasty enables lung parenchyma preservation, potentially avoiding pneumonectomy.

    Conclusions:

    • Extended resection with bronchovasculoplasty is a viable option to avoid pneumonectomy in select lung cancer patients.
    • Ex vivo bench surgery offers advantages in lung graft handling and preservation.
    • The clinical utility of this challenging surgical approach requires further assessment.