Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Elements: Chemical Symbols and Isotopes02:31

Elements: Chemical Symbols and Isotopes

126.4K
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
126.4K
DNA as a Genetic Template02:05

DNA as a Genetic Template

27.9K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
27.9K
The Periodic Table03:25

The Periodic Table

115.9K
As early chemists discovered more elements, they realized that various elements could be grouped by their similar chemical behaviors. One such grouping includes lithium (Li), sodium (Na), and potassium (K). All of these elements are shiny, conduct heat and electricity well, and have similar chemical properties. A second grouping includes calcium (Ca), strontium (Sr), and barium (Ba), which also are shiny, good conductors of heat and electricity, and have chemical properties in common. However,...
115.9K
Genetic Lingo01:11

Genetic Lingo

114.9K
Overview
114.9K
Karyotyping01:17

Karyotyping

68.5K
Overview
68.5K
The Wave Nature of Light02:12

The Wave Nature of Light

61.5K
The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion.
61.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychoactive Medication, Violence, and Variant Alleles for Cytochrome P450 Genes.

Journal of personalized medicine·2021
Same author

REPRODUCTIVE ISOLATION IN SONORAN DESERT DROSOPHILA.

Evolution; international journal of organic evolution·2017
Same author

Comparisons of yeast florae from natural substrates and larval guts of southwestern Drosophila.

Oecologia·2017
Same author

The relevance of cytochrome P450 polymorphism in forensic medicine and akathisia-related violence and suicide.

Journal of forensic and legal medicine·2016
Same author

SPERM HY-LITER™ for the identification of spermatozoa from sexual assault evidence.

Forensic science international. Genetics·2014
Same author

Capillary electrophoresis sequencing: maximum read length at minimal cost.

BioTechniques·2002
Same journal

Adherence to international pharmacogenomic recommendations in pediatric cancer care: a cohort analysis embedded within the MARVEL-PIC randomized trial.

Pharmacogenomics·2026
Same journal

Closely similar tacrolimus morning troughs and graft function across the recipients' common <i>ABCB1</i> polymorphisms (<i>c.2677G>T/A</i>, <i>c.1236C>T</i>, <i>c.3435C>T</i>) early after renal transplantation.

Pharmacogenomics·2026
Same journal

Pharmacogenomics for stratified antidepressant treatment in major depressive disorder: evidence, limits and a roadmap for clinical use.

Pharmacogenomics·2026
Same journal

Guidance from an informed public on collecting and sharing PGx test results for major depressive disorder: "It's no different from your blood type".

Pharmacogenomics·2026
Same journal

Optimizing pharmacogenomics workflows: a qualitative evaluation of clinical service delivery models.

Pharmacogenomics·2026
Same journal

Combinations of single gene predictors with AI-driven polygenic precision therapies in cardiovascular diseases.

Pharmacogenomics·2026
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

Training Synesthetic Letter-color Associations by Reading in Color
10:27

Training Synesthetic Letter-color Associations by Reading in Color

Published on: February 20, 2014

23.4K

Letter to the Editor.

Selma Jm Eikelenboom-Schieveld1,2, James C Fogleman2

  • 1Independent Forensic Services LLC, 32796 Edward Drive, Conifer, CO 80433, USA.

Pharmacogenomics
|September 1, 2018
PubMed
Summary
This summary is machine-generated.

Genetic variations in CYP450 enzymes may influence aggressive behavior in patients taking selective serotonin reuptake inhibitors. Understanding these genetic factors could personalize antidepressant treatment for better outcomes.

Area of Science:

  • Pharmacogenomics
  • Neuroscience
  • Psychiatry

Background:

  • Selective serotonin reuptuptake inhibitors (SSRIs) are commonly prescribed antidepressants.
Keywords:
CYP450 genotypeSSRIsaggressive behaviorphenoconversion

More Related Videos

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
09:22

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors

Published on: February 28, 2021

6.0K
Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids
07:14

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids

Published on: May 16, 2025

697

Related Experiment Videos

Last Updated: Feb 5, 2026

Training Synesthetic Letter-color Associations by Reading in Color
10:27

Training Synesthetic Letter-color Associations by Reading in Color

Published on: February 20, 2014

23.4K
Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
09:22

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors

Published on: February 28, 2021

6.0K
Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids
07:14

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids

Published on: May 16, 2025

697
  • Aggressive behavior is a potential side effect of SSRI treatment in some individuals.
  • Cytochrome P450 (CYP450) enzymes play a crucial role in metabolizing SSRIs.