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Updated: Feb 5, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Identification of Senior At Risk scale predicts 30-day mortality among older patients with acute heart failure
F J Martín-Sánchez1, G Llopis García1, M González-Colaço Harmand2
1Servicio de Urgencias, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Universidad Complutense de Madrid, Madrid, España.
Objective:
To assess the value of frailty screening tool (Identification of Senior at Risk [ISAR]) in predicting 30-day mortality risk in older patients attended in emergency department (ED) for acute heart failure (AHF).
Design:
Observational multicenter cohort study.
Setting:
OAK-3 register.
Subjects:
Patients aged ≥65 years attended with ADHF in 16 Spanish EDs from January to February 2016.
Intervention:
No.
Variables:
Variable of study was ISAR scale. The outcome was all-cause 30-day mortality.
Results:
We included 1059 patients (mean age 85±5,9 years old). One hundred and sixty (15.1%) cases had 0-1 points, 278 (26.3%) 2 points, 260 (24.6%) 3 points, 209 (19.7%) 4 points, and 152 (14.3%) 5-6 points of ISAR scale. Ninety five (9.0%) patients died within 30 days. The percentage of mortality increased in relation to ISAR category (lineal trend P value <.001). The area under curve of ISAR scale was 0.703 (95%CI 0.655-0.751; P<.001). After adjusting for EFFECT risk categories, we observed a progressive increase in odds ratios of ISAR scale groups compared to reference (0-1 points).
Conclusions:
scale is a brief and easy tool that should be considered for frailty screening during initial assessment of older patients attended with AHF for predicting 30-day mortality.
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