Gorlin-Goltz Syndrome: A Rare Case Report.
Naveen N Kumar1, S Padmashree1, T R Jyotsna1
1Departments of Oral Medicine and Radiology, Vydehi Institute of Dental Sciences and Research Centre, Bengaluru, Karnataka, India.
Gorlin-Goltz syndrome (GGS) is a rare genetic disorder causing jaw cysts and other abnormalities. Early diagnosis is crucial to prevent severe complications like maxillofacial deformities.
Area of Science:
- Genetics
- Oral and Maxillofacial Surgery
- Dermatology
Background:
- Gorlin-Goltz syndrome (GGS) is an autosomal dominant disorder.
- Characterized by multiple odontogenic keratocysts (OKCs), bifid ribs, and other abnormalities.
- Incidence is estimated between 1 in 57,000 to 1 in 256,000.
Observation:
- A 25-year-old male presented with facial swelling.
- Clinical, histological, and imaging findings led to a GGS diagnosis.
- Odontogenic keratocysts (OKCs) are often the initial manifestation.
Findings:
- The case highlights the diagnostic process for GGS.
- Correlating clinical, histological, and imaging data is essential.
- Early identification of GGS is critical.
Implications:
- Early diagnosis of GGS can prevent severe complications.
- Timely intervention can mitigate maxillofacial deformities.
- This case underscores the importance of recognizing GGS symptoms.
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