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Vancomycin-induced red man syndrome presentation in a preterm infant
Silvia Martini1, Rosina Alessandroni1, Santo Arcuri1
1Neonatology and Neonatal Intensive Care Unit, Department of Medical and Surgical Sciences (DIMEC), St. Orsola-Malpighi Hospital-University of Bologna, Bologna, Italy.
Pediatric Dermatology
|September 1, 2018
Summary
Vancomycin can cause Red Man Syndrome in newborns, presenting as a rash and irritability. Promptly stopping the infusion helps symptoms resolve, highlighting the need for awareness in neonatal care.
Area of Science:
- Neonatal Medicine
- Pharmacology
- Pediatric Infectious Diseases
Background:
- Vancomycin is a critical antibiotic for treating serious neonatal infections.
- Femoral osteomyelitis is a challenging condition in premature infants.
Observation:
- A premature male infant developed a widespread erythematous rash and irritability on vancomycin therapy.
- Symptoms rapidly improved after the vancomycin infusion was discontinued.
Findings:
- The infant's presentation is consistent with Red Man Syndrome, a known adverse reaction to vancomycin.
- This reaction, though rare in neonates, requires prompt recognition and management.
Implications:
- Increased awareness of Red Man Syndrome is crucial for neonatologists and pediatricians.
- Early identification and intervention can prevent severe complications of this vancomycin adverse drug reaction.
Keywords:
adverse drug reactionantibiotic therapyneonateosteomyelitisprematurityred man syndromevancomycin hypersensitivityMore Related Videos
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