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Initial experience with EUS-guided microbiopsy forceps in diagnosing pancreatic cystic lesions: A multicenter

Bojan Kovacevic1, John Gásdal Karstensen2, Roald Flesland Havre3

  • 1Division of Endoscopy, Gastro Unit, Copenhagen University Hospital Herlev, Copenhagen, Denmark.

Endoscopic Ultrasound
|September 1, 2018
PubMed
Abstract

Insights

A novel microbiopsy forceps for endoscopic ultrasound (EUS)-guided pancreatic cyst evaluation shows promising feasibility. This tool achieved good technical and clinical success rates in a multicenter study.

Area of Science:

  • Gastroenterology
  • Endoscopic Ultrasound (EUS)
  • Pancreatic Pathology

Background:

  • Pancreatic cystic lesions pose diagnostic challenges.
  • Endoscopic ultrasound (EUS) is crucial for evaluating pancreatic cysts.
  • Histological analysis is key for accurate diagnosis.

Purpose of the Study:

  • To evaluate the utility of a novel through-the-needle microbiopsy forceps for EUS-guided pancreatic cyst wall sampling.
  • To assess the feasibility and performance of this new instrument in a multicenter setting.

Main Methods:

  • Retrospective analysis of patients undergoing EUS-guided microbiopsy for pancreatic cysts across six international centers.
  • Data collected included patient demographics, EUS findings, technical/clinical success rates, and histopathological results.

Main Results:

  • Technical success rate of 85.7% (24/28 patients).
  • Histopathological specimens were of good quality, aiding diagnosis in 71.4% (20/28 patients).
  • An acceptable safety profile with 10.7% (3/28) adverse events.

Conclusions:

  • The novel microbiopsy forceps demonstrates feasibility for EUS-guided pancreatic cyst diagnosis.
  • Acceptable technical and clinical success rates were observed in this multicenter study.
  • Further prospective research is needed to compare its diagnostic efficacy against existing methods.
Keywords:
EUS-FNAIPMNmicrobiopsy forcepsmoraypancreatic cancerpancreatic cysts

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