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Updated: Feb 5, 2026
Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Recent advances in the synthesis of azaphenalene alkaloids: first enantioselective approaches
Sílvia Alujas-Burgos1, Pau Bayón, Marta Figueredo
1Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. marta.figueredo@uab.es.
Abstract:
Azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in the field of biological pest control, has led to several research groups developing synthetic sequences to prepare these compounds. The main purpose of the present review is to provide an update of the more recent synthetic progress towards these alkaloids, including the pioneering enantioselective approaches to chiral congeners.
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