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Updated: Feb 5, 2026

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Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
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[NATURAL ORIFICE TRANSLUMENAL ENDOSCOPIC SURGERY]
Nihon Geka Gakkai Zasshi
|September 1, 2018
Summary
Natural orifice translumenal endoscopic surgery (NOTES) has advanced significantly since 2007, with common procedures like cholecystectomy and appendectomy. Future development requires new instruments and understanding the benefits of reduced surgical wounds.
Area of Science:
- Minimally Invasive Surgery
- Gastroenterology
- Endoscopic Procedures
Background:
- Natural orifice translumenal endoscopic surgery (NOTES) emerged in 2007.
- Thousands of patients globally have undergone NOTES procedures.
- This review examines the current status and future trajectory of NOTES.
Purpose of the Study:
- To summarize and highlight the current status of NOTES.
- To outline future directions and necessary developments for NOTES.
- To discuss the significance of reduced surgical wounds in NOTES.
Main Methods:
- Review of existing clinical applications and procedures.
- Analysis of common NOTES procedures like cholecystectomy and appendectomy.
- Examination of direct-target NOTES such as per oral endoscopic myotomy (POEM) and transanal total mesorectal excision.
Main Results:
- Hybrid NOTES, primarily transvaginal cholecystectomy and appendectomy, are most common.
- Direct-target NOTES (e.g., POEM) are rapidly expanding due to minimal organ injury.
- Japan has established a clinical registration system for safe NOTES application, featuring advanced endoscopic techniques.
Conclusions:
- NOTES is evolving into a new minimally invasive treatment modality.
- Further development of instruments and assessment of social needs are crucial for pure NOTES.
- The significance of reduced surgical wounds requires further determination.
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