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Published on: August 14, 2019
Treatment of upper urinary tract stones with flexible ureteroscopy in children
Jing Xiao1, Xiangyu Wang1, Jun Li1
1Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Insights
Flexible ureteroscopy (FURS) with holmium laser lithotripsy effectively treats pediatric upper urinary tract stones. This safe procedure achieved an 89% stone-free rate in 100 children, with minor complications.
Area of Science:
- Pediatric Urology
- Endourology
- Nephrolithiasis Treatment
Background:
- Upper urinary tract stones in children pose a significant clinical challenge.
- Flexible ureteroscopy (FURS) has emerged as a minimally invasive treatment option.
- Holmium laser lithotripsy offers precise stone fragmentation capabilities.
Purpose of the Study:
- To evaluate the efficacy and safety of FURS combined with holmium laser lithotripsy.
- To assess the stone-free rate and complication profile in pediatric patients.
- To identify factors influencing treatment outcomes in children with upper tract stones.
Main Methods:
- Retrospective analysis of 100 pediatric patients undergoing FURS with holmium laser lithotripsy.
- Preoperative stenting with a double-J stent was performed in all cases.
- Data on operative parameters, stone characteristics, and postoperative outcomes were collected and analyzed.
Main Results:
- An overall stone-free rate of 89% was achieved after a single operation.
- Mean stone diameter was 1.49 cm; average operative time was 30.8 minutes.
- The most common complications were postoperative hematuria (64%) and urinary tract infection (7.1%); no ureteral perforations occurred.
Conclusions:
- FURS combined with holmium laser lithotripsy is an effective and safe treatment for pediatric upper urinary tract stones.
- Stone size and staghorn calculi were significantly associated with the stone-free rate.
- The procedure demonstrates a favorable safety profile with manageable complications in the pediatric population.
Introduction:
This single-centre, retrospective study aimed to assess the efficacy and safety of flexible ureteroscopy (FURS) combined with holmium laser lithotripsy in treating children with upper urinary tract stones.
Methods:
From June 2014 to October 2015, a total of 100 children (74 boys and 26 girls) with upper urinary tract stones were treated using FURS. A 4.7 Fr double-J stent was placed two weeks before operation. Patients were considered stone-free when the absence of residual fragments was observed on imaging studies. The preoperative, operative, and postoperative data of the patients were retrospectively analyzed.
Results:
A total of 100 pediatric patients with a mean age of 3.51±1.82 years underwent 131 FURS and holmium laser lithotripsy. Mean stone diameter was 1.49±0.92 cm. Average operation time was 30.8 minutes (range 15-60). The laser power was controlled between 18 and 32 W, and the energy maintained between 0.6 and 0.8 J at any time; laser frequency was controlled between 30 and 40 Hz. Complications were observed in 69 (69.0 %) patients and classified according to the Clavien system. Postoperative hematuria (Clavien I) occurred in 64 (64.0 %) patients. Postoperative urinary tract infection with fever (Clavien II) was observed in 8/113 (7.1%) patients. No ureteral perforation and mucosa avulsion occurred. The overall stone-free rate of single operation was 89/100 (89%). Stone diameter and staghorn calculi were significantly associated with stone-free rate.
Conclusions:
FURS and holmium laser lithotripsy is effective and safe in treating children with upper urinary tract stones.
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