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Published on: March 27, 2018
Left ventricular function recovery after revascularization: comparative effects of percutaneous coronary intervention
Janet M C Ngu1, Marc Ruel1, Louise Y Sun
1Division of Cardiac Surgery.
Insights
Heart failure with recovered ejection fraction (HFrecEF) shows improved survival. Coronary artery bypass grafting (CABG) may offer greater left ventricular ejection fraction (LVEF) recovery than percutaneous coronary intervention (PCI) in ischemic cardiomyopathy.
Area of Science:
- Cardiology
- Heart Failure Research
Background:
- Heart failure with recovered ejection fraction (HFrecEF) is a recognized phenotype.
- HFrecEF is linked to enhanced survival and quality of life.
Purpose of the Study:
- To review HFrecEF.
- To compare percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) effects on left ventricular ejection fraction (LVEF) recovery in ischemic cardiomyopathy.
Main Methods:
- Literature review of HFrecEF.
- Comparative analysis of PCI vs. CABG for LVEF recovery.
Main Results:
- Emerging data suggests LV functional recovery is achievable.
- CABG may yield greater LVEF improvement than PCI.
- Direct comparative studies are limited.
Conclusions:
- LVEF recovery is a significant outcome with survival benefits.
- Further randomized trials are necessary to compare PCI and CABG for LVEF recovery in ischemic cardiomyopathy.
Purpose Of Review:
In 2013, heart failure with recovered ejection fraction (HFrecEF) was introduced as a new heart failure phenotype. This review provides an overview of HFrecEF and the comparative effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on left ventricular ejection fraction (LVEF) recovery in patients with ischemic cardiomyopathy.
Recent Findings:
There has been emerging data indicating that LV functional recovery is possible and HFrecEF is associated with improved survival and better quality of life. CABG may be associated with larger improvement in LVEF when compared with PCI. However, there is significant paucity of studies, which directly compare the impact of PCI and CABG on LVEF recovery in the setting of ischemic cardiomyopathy.
Summary:
LVEF recovery is emerging as an important outcome with demonstrated survival and quality-of-life benefits. Future randomized clinical trials comparing the impact of contemporary PCI and CABG on LVEF recovery are needed in patients with ischemic cardiomyopathy.
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