Related Experiment Video

Updated: Feb 5, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

4.4K

Single patch closure of multiple VSDs through right atrial approach

Nagarajan Muthialu1, Soundaravalli Balakrishnan1, Rajani Sundar1

  • 1Departments of Cardiothoracic Surgery, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India; Departments of Anaesthesiology, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India.

Indian Heart Journal
|September 2, 2018
PubMed

Insights

Single patch closure effectively treated multiple ventricular septal defects (VSD) in children, avoiding ventriculotomy. This surgical approach through the right atrium offers a viable option for complex VSD cases.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Multiple ventricular septal defects (VSD) present significant surgical challenges, often necessitating ventriculotomy.
  • Traditional surgical approaches for multiple VSDs can be complex and carry substantial risks.

Discussion:

  • This study presents a novel technique using a single Gore-Tex patch for the closure of multiple VSDs in pediatric patients.
  • The transatrial approach facilitated the closure, avoiding the need for ventriculotomy and its associated complications.

Key Insights:

  • Successful closure of multiple VSDs was achieved in 4 pediatric patients using a single patch via the right atrium.
  • The procedure resulted in no operative deaths and a short intensive care unit stay, highlighting its safety and efficacy.
  • This technique expands the surgical options for managing complex congenital heart defects.

Outlook:

  • Further research should explore the long-term outcomes and broader applicability of this single-patch closure technique for multiple VSDs.
  • This approach may offer a less invasive alternative for select pediatric patients with multiple VSDs.
  • Continued refinement of surgical strategies for complex VSDs is crucial for improving patient outcomes.

Keywords:
Multiple VSDPatch closureVSD closure

More Related Videos

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

84.6K
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

34.1K

Related Concept Videos

Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.0K
Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...
246
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.3K
Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
38.1K
Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
6.6K
Multiple Regression01:25

Multiple Regression

Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.0K