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Related Concept Videos

Autonomic Nervous System01:22

Autonomic Nervous System

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The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control.
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...
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The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
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Disorders of the Autonomic Nervous System01:18

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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Measuring Cardiac Autonomic Nervous System ANS Activity in Children
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Cell-Type Identification in the Autonomic Nervous System.

Di-Shi Liu1, Tian-Le Xu2

  • 1Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

Neuroscience Bulletin
|September 2, 2018
PubMed
Summary

Understanding autonomic nervous system (ANS) neuronal subpopulations is crucial for treating related disorders. This review covers technologies for peripheral neuronal tracing and profiling to map ANS connectivity.

Keywords:
Autonomic nervous systemCell-type diversityGenetic markerMolecular profilingNeuronal tracing

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Area of Science:

  • Neuroscience
  • Autonomic Nervous System Research
  • Cellular and Molecular Biology

Background:

  • The autonomic nervous system (ANS) regulates vital physiological functions and its dysfunction leads to various disorders.
  • Current understanding of autonomic neuronal subpopulations and their precise connectivity remains limited.
  • The complexity and heterogeneity of autonomic neurons present significant challenges to research.

Purpose of the Study:

  • To review established and emerging technologies for peripheral neuronal tracing and profiling.
  • To facilitate the identification and classification of autonomic neuronal subgroups.
  • To provide insights into the operating mechanisms, advantages, and applications of these technologies.

Main Methods:

  • Review of established and cutting-edge technologies for peripheral neuronal tracing.
  • Analysis of profiling techniques for autonomic neurons.
  • Discussion of technological mechanisms, benefits, and applications.

Main Results:

  • Identification of key technologies for studying autonomic neuronal structure and function.
  • Evaluation of the strengths and weaknesses of different tracing and profiling methods.
  • Discussion of how these technologies can advance the mapping of autonomic neural circuits.

Conclusions:

  • Advanced tracing and profiling technologies are essential for overcoming the heterogeneity of autonomic neurons.
  • Improved understanding of autonomic neuronal subpopulations and connectivity will aid in diagnosing and treating ANS-related disorders.
  • This review provides a comprehensive overview to guide future research in autonomic neuroscience.