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Updated: Feb 5, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
Brain magnetic resonance imaging using a customized vacuum shape-keeping immobilizer without sedation in preterm
Kenichiro Yamamura1, Yasuo Takatsu2, Tosiaki Miyati3
1Department of Radiology, Osaka Medical College Hospital, 2-7, Daigaku-machi, Takatsuki City, Osaka 569-8686, Japan; Division of Health Sciences, Kanazawa University Graduate School of Medical Sciences, 5-11-80 Kodatsuno, Kanazawa 920-0942, Japan.
Objective:
To validate that a customized vacuum shape-keeping immobilizer (VaSKI) can be used in preterm infants without sedation.
Methods:
Preterm infants who underwent brain MRI from February 2008 to March 2017 at Osaka Medical College Hospital were retrospectively assigned to the sedation group (February 2008 to September 2013, n = 64) or VaSKI group (October 2013 to November 2016, n = 64). The examination success rates and diagnosable case classification were determined by pediatricians and radiologists. We compared the time from preparation to examination completion between the groups. Furthermore, we measured the time from immobilization to sleep in the preterm infants in the VaSKI group.
Results:
The examination success rate was 90.6% in both of the groups. The median (interquartile range) times of preparation were 24.0 (15.3) and 18.0 (13.0) min in the sedation and VaSKI groups, respectively. In the VaSKI group, the time from immobilization to sleep was within 3 min in 87.1% of the preterm infants.
Conclusions:
The brain MRI examination success rates and motion artifact suppression effects were equivalent between the groups, whereas the time from preparation to examination completion was much shorter in the VaSKI group. Therefore, the VaSKI was validated as an immobilizer for MRI in preterm infants without using sedation.
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