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A luminescence nanosensor for Ornidazole detection using graphene quantum dots entrapped in silica molecular
Mina Mehrzad-Samarin1, Farnoush Faridbod2, Mohammad Reza Ganjali3
1School of Chemistry, Alborz Campus, University of Tehran, Tehran, Iran.
Abstract:
A luminescence nanosensor has been developed for analysis of Ornidazole in biological samples using graphene-quantum-dot-embedded silica molecular imprinted polymer (GQD-SMIP) as a selective probe for this analyte. The GQD-SMIP was found to possess a strong fluorescent emission at 450 nm upon excitation at 365 nm. This emission was found to linearly quench in the presence of Ornidazole in a concentration range of 0.75 to 30 μM. A detection limit of 0.24 μM was reached using the probe and the sensor was successfully used in the determination of the analyte in plasma samples.
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