Related Experiment Video
Updated: Feb 5, 2026

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells
Published on: February 23, 2024
Acrocutaneous metastasis - A rare presentation
Srujana Reddy Mandadi1, Annappa Kudva1
1Department of General Surgery, Kasturba Medical College Manipal University, Manipal, India.
A rare case of acrocutaneous metastasis from base of tongue squamous cell carcinoma occurred in an 84-year-old male. This highlights the importance of investigating skin nodules in head and neck cancer patients.
Area of Science:
- Oncology
- Dermatology
- Head and Neck Surgery
Background:
- Cutaneous metastasis from head and neck cancers is uncommon.
- Acrocutaneous metastasis, particularly from the base of the tongue, is exceptionally rare.
Purpose of the Study:
- To report a rare case of acrocutaneous metastasis from base of tongue squamous cell carcinoma.
- To emphasize the diagnostic considerations for skin lesions in head and neck cancer patients.
Main Methods:
- Case presentation of an 84-year-old male with moderately differentiated squamous cell carcinoma of the base of tongue.
- Patient received palliative chemoradiation for lung and liver metastases.
- Surgical amputation of the affected finger followed by histopathological examination.
Main Results:
- Histopathology confirmed moderately differentiated squamous cell carcinoma metastasis to the right 5th finger.
- The metastasis presented as an ulcero-proliferative growth, initially suspected as osteomyelitis.
- This rare metastasis occurred shortly after completion of treatment.
Conclusions:
- Skin metastasis from base of tongue cancer can occur even after treatment.
- Fine needle aspiration cytology is crucial for evaluating cutaneous nodules in head and neck cancer patients, regardless of apparent benignity.
Related Concept Videos
Self-Presentation
Self-Presentation: Self-Monitoring and Self-Handicapping
Strategies of Self-Presentation I: Strategic Self-Presentation
Processes of Self-Presentation
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Strategies of Self-Presentation II: Self-Verification

