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Primary uterine angiosarcoma with "rhabdoid morphology": A case report
J S Gandhi1, M Kamboj, G Gupta
1Rajiv Gandhi Cancer Institute & Research Center, Department of Histopathology & Cytopathology, Sector 5 Rohini, New Delhi-85, India. jgandhi79@gmail.com.
Introduction:
Primary uterine angiosarcoma is a very rare tumour, with only 23 cases described till now. It is a malignant tumour with cells variably recapitulating the morphologic features of an endothelium and expressing immunohistochemical markers of endothelial cells. In general, it is a bulky neoplasm and frequently is at advance stage of disease at presentation. In general, patients with uterine angiosarcoma tend to have a poorer prognosis, mostly related to the aggressive nature and the metastatic potential of these tumours.
Case Report:
We report a rare case of primary uterine angiosarcoma with unusual rhabdoid morphology in a 41-year-old female, who underwent radical hysterectomy and died of disease after 4 months of treatment.
Discussion:
We described the differential diagnosis of primary angiosarcoma of the uterus that can pose a diagnostic challenge.
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