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Diagnostic challenges in a patient with calciphylaxia - a case report
Violeta Claudia Bojincă1, Mihai Bojincă, Cristina Ileana Iosif
1Department of Internal Medicine and Rheumatology, "Dr. Ion Cantacuzino" Hospital, Bucharest, Romania; vmbojinca@yahoo.com.
Abstract:
Calciphylaxis is a condition with unclear etiopathogeny with vascular calcifications and thrombotic occlusion that lead to necrotic lesions. It is usually described in patients with end-stage renal disease (ESRD), but also in other conditions. The mortality rate is high, due to sepsis and internal organ failure. We present the case of a patient with multiple comorbidities (ESRD, diabetes, hypertension, Mönckeberg's sclerosis) with problems of differential diagnostic due to the necrotic lesions that mislead initially to systemic lupus erythematosus (SLE) with necrotizing vasculitis.
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