Related Experiment Video
Updated: Feb 5, 2026

Orthotopic Implantation of Patient-Derived Cancer Cells in Mice Recapitulates Advanced Colorectal Cancer
Published on: February 10, 2023
Metastatic Colorectal Cancer to the Peritoneum: Current Treatment Options
Nikolaos Vassos1, Pompiliu Piso2
1Department of Surgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 12, 91054, Erlangen, Germany. nikolaos.vassos@uk-erlangen.de.
Opinion Statement:
Peritoneal metastases (PM) are common in advanced-stage colorectal cancer (CRC) patients representing the second most common metastatic site of CRC. In the past, this clinical situation was treated with palliative intent. The introduction of new chemotherapeutic and targeted biologic agents has improved the prognosis of patients with metastatic colorectal cancer. However, the inclusion of treatment options such as cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as inherent components of a multidisciplinary treatment was evolving for the management of these patients. Notably, the surgical approach of CRS/HIPEC has been effective offering a prolonged survival with curative intent in patients with colorectal PM. This article reviews and highlights the recent evidence of CRS and HIPEC as well as current research going on in this form of locoregional treatment in the setting of peritoneal metastases of colorectal cancer.
Related Concept Videos
Peritoneum
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Treatment Resistant Cancers
Electrical Current
Current Density
Eddy Currents
Other major applications of eddy currents appear in metal detectors and the braking systems of trains and roller...
Displacement Current

